Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4409801 | 0.93 | HTT (0.66) | HTTMAPTMEN1THRBKMT2A | |
| SCHEMBL16218012 | 0.90 | USP2 (0.69) | HTTMAPTMEN1THRBKMT2A | |
| SCHEMBL28189988 | 0.90 | USP2 (0.69) | HTTMAPTMEN1THRBKMT2A | |
| SCHEMBL20055683 | 0.89 | USP2 (0.56) | HTTMAPTMEN1THRBKMT2A | |
| SCHEMBL27968085 | 0.87 | TSHR (0.63) | HTTMAPTMEN1THRBKMT2A | |
| Triethylene Glycol SCHEMBL28094364 | 0.87 | TSHR (0.63) | HTTMAPTMEN1THRBKMT2A | |
| SCHEMBL28165908 | 0.86 | USP2 (0.69) | HTTMAPTMEN1THRBKMT2A | |
| SCHEMBL27280251 | 0.86 | USP2 (0.69) | HTTMAPTMEN1THRBKMT2A | |
| Di(Hydroxyethyl)Ether SCHEMBL1985189 | 0.86 | TSHR (0.56) | HTTMAPTMEN1THRBKMT2A | |
| SCHEMBL6689967 | 0.86 | THRB (0.48) | HTTMAPTMEN1THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104479807-B | Lubricating composition containing antiwear additive | 路博润公司 | 2017-11-17 | — | — | CN | disclosed |