Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 15/20 | 0.44 |
| ▸ | CNR1 | P21554 | 10/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1987373 | 0.93 | CNR2 (0.43) | LMNACNR2CNR1 | |
| SCHEMBL1990290 | 0.92 | CNR2 (0.44) | LMNACNR2CNR1 | |
| SCHEMBL1983824 | 0.87 | CNR2 (0.45) | LMNACNR2CNR1 | |
| SCHEMBL1985983 | 0.86 | CNR2 (0.50) | LMNACNR2CNR1 | |
| SCHEMBL1985554 | 0.86 | MAPT (0.39) | LMNACNR1 | |
| SCHEMBL1985913 | 0.85 | CNR2 (0.59) | LMNACNR2CNR1 | |
| SCHEMBL1982826 | 0.84 | CNR2 (0.54) | CNR2CNR1 | |
| SCHEMBL1984047 | 0.83 | CNR2 (0.59) | LMNACNR2CNR1 | |
| SCHEMBL8779197 | 0.83 | CNR2 (0.61) | CNR2CNR1 | |
| SCHEMBL1989275 | 0.81 | CNR2 (0.43) | LMNACNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1602656-B1 | PYRAZOLE DERIVATIVES HAVING AFFINITY FOR CB1 AND/OR CB2 RECEPTORS | NEUROSCIENZE PHARMANESS S C A R L (IT) | 2011-06-29 | — | — | EP | claimed |