SCHEMBL8779197

SCHEMBL8779197

Cc1c(OC(=O)O)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1

nearest known ligand 0.62

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 13/20 0.61
CNR1 P21554 6/20 0.60
PPARA Q07869 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1985983 0.84 CNR2 (0.50) CNR2CNR1
SCHEMBL1985199 0.83 LMNA (0.44) CNR2CNR1
SCHEMBL1985913 0.83 CNR2 (0.59) CNR2CNR1
SCHEMBL1987373 0.82 CNR2 (0.43) CNR2CNR1
SCHEMBL1990290 0.82 CNR2 (0.44) CNR2CNR1
SCHEMBL1984047 0.82 CNR2 (0.59) CNR2CNR1
SCHEMBL924033 0.81 CNR2 (0.76) CNR2CNR1PPARA
SCHEMBL30571219 0.81 CNR2 (0.76) CNR2CNR1PPARA
Hydrochloric Acid SCHEMBL3002214 0.81 CNR2 (0.74) CNR2CNR1PPARA
SCHEMBL1009704 0.80 CNR2 (0.69) CNR2CNR1PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0656354-B1 Substituted N-piperidino 3-pyrazolecarboxamide SANOFI SA (FR) 1997-06-04 EP claimed