Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 6/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28960390 | 0.86 | USP2 (0.40) | USP2SMN1; SMN2EPHX2RECQLCCR2 | |
| SCHEMBL21590472 | 0.86 | USP2 (0.40) | USP2SMN1; SMN2EPHX2RECQLCCR2 | |
| SCHEMBL21590471 | 0.86 | USP2 (0.40) | USP2SMN1; SMN2EPHX2RECQLCCR2 | |
| SCHEMBL2426932 | 0.85 | GPR119 (0.42) | USP2SMN1; SMN2MGLLEPHX2GPR119 | |
| SCHEMBL18481140 | 0.83 | USP2 (0.46) | USP2SMN1; SMN2MGLLEPHX2RECQL | |
| SCHEMBL16419553 | 0.83 | USP2 (0.46) | USP2SMN1; SMN2MGLLEPHX2RECQL | |
| SCHEMBL20411386 | 0.83 | USP2 (0.46) | USP2SMN1; SMN2MGLLEPHX2RECQL | |
| SCHEMBL897951 | 0.83 | USP2 (0.46) | USP2SMN1; SMN2MGLLEPHX2RECQL | |
| SCHEMBL20411385 | 0.83 | USP2 (0.46) | USP2SMN1; SMN2MGLLEPHX2RECQL | |
| SCHEMBL2428569 | 0.82 | USP2 (0.45) | USP2SMN1; SMN2MGLLEPHX2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026371-A1 | DUAL NAV1.2/5HT2A INHIBITORS FOR TREATING CNS DISORDERS | SUNOVION PHARMACEUTICALS INC. (US) | 2018-02-08 | — | — | WO | disclosed |