Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.56 |
| ▸ | DRD4 | P21917 | 4/20 | 0.56 |
| ▸ | DRD3 | P35462 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 7/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 7/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21071707 | 1.00 | DRD2 (0.56) | DRD2DRD4DRD3TSHRMEN1 | |
| SCHEMBL21071969 | 1.00 | DRD2 (0.56) | DRD2DRD4DRD3TSHRMEN1 | |
| SCHEMBL21145808 | 1.00 | DRD2 (0.56) | DRD2DRD4DRD3TSHRMEN1 | |
| SCHEMBL21071709 | 1.00 | DRD2 (0.56) | DRD2DRD4DRD3TSHRMEN1 | |
| SCHEMBL21071533 | 0.94 | DRD2 (0.49) | DRD2DRD4DRD3TSHRMEN1 | |
| SCHEMBL21071534 | 0.94 | DRD2 (0.49) | DRD2DRD4DRD3TSHRMEN1 | |
| SCHEMBL21071868 | 0.94 | DRD2 (0.49) | DRD2DRD4DRD3TSHRMEN1 | |
| SCHEMBL21071536 | 0.94 | DRD2 (0.49) | DRD2DRD4DRD3TSHRMEN1 | |
| SCHEMBL21071528 | 0.94 | DRD2 (0.49) | DRD2DRD4DRD3TSHRMEN1 | |
| SCHEMBL21071527 | 0.94 | DRD2 (0.49) | DRD2DRD4DRD3TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026371-A1 | DUAL NAV1.2/5HT2A INHIBITORS FOR TREATING CNS DISORDERS | SUNOVION PHARMACEUTICALS INC. (US) | 2018-02-08 | — | — | WO | disclosed |