Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21142602 | 0.97 | HPGD (0.55) | HPGDGPR119EPHX1BACE1CTSD | |
| SCHEMBL19852544 | 0.97 | HPGD (0.50) | HPGDGPR119EPHX1BACE1CTSD | |
| SCHEMBL28131719 | 0.91 | MEN1 (0.49) | HPGDGPR119BACE1CTSDMEN1 | |
| SCHEMBL14368873 | 0.89 | MEN1 (0.50) | HPGDGPR119BACE1CTSDMEN1 | |
| SCHEMBL14368864 | 0.89 | MEN1 (0.50) | HPGDGPR119BACE1CTSDMEN1 | |
| SCHEMBL4424219 | 0.89 | MEN1 (0.50) | HPGDGPR119BACE1CTSDMEN1 | |
| SCHEMBL20128944 | 0.89 | GPR119 (0.57) | HPGDGPR119MEN1KMT2AHTT | |
| SCHEMBL7512359 | 0.87 | GPR119 (0.56) | HPGDGPR119EPHX1FAAHPKM | |
| SCHEMBL20310041 | 0.85 | MEN1 (0.51) | HPGDGPR119BACE1CTSDMEN1 | |
| SCHEMBL8151168 | 0.83 | GPR119 (0.55) | HPGDGPR119EPHX1FAAHPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026371-A1 | DUAL NAV1.2/5HT2A INHIBITORS FOR TREATING CNS DISORDERS | SUNOVION PHARMACEUTICALS INC. (US) | 2018-02-08 | — | — | WO | disclosed |