Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | PRMT5 | O14744 | 10/20 | 0.56 |
| ▸ | WDR77 | Q9BQA1 | 10/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21071450 | 0.83 | GAA (0.67) | MEN1GAAKMT2AALDH1A1PRMT5 | |
| SCHEMBL21071669 | 0.83 | GAA (0.67) | MEN1GAAKMT2AALDH1A1PRMT5 | |
| SCHEMBL19852510 | 0.83 | GAA (0.67) | MEN1GAAKMT2AALDH1A1PRMT5 | |
| SCHEMBL21071801 | 0.83 | GAA (0.67) | MEN1GAAKMT2AALDH1A1PRMT5 | |
| SCHEMBL21071615 | 0.83 | GAA (0.67) | MEN1GAAKMT2AALDH1A1PRMT5 | |
| SCHEMBL21071617 | 0.83 | GAA (0.67) | MEN1GAAKMT2AALDH1A1PRMT5 | |
| SCHEMBL21071449 | 0.83 | GAA (0.67) | MEN1GAAKMT2AALDH1A1PRMT5 | |
| SCHEMBL21071707 | 0.81 | DRD2 (0.56) | MEN1GAAKMT2AALDH1A1PRMT5 | |
| SCHEMBL21071969 | 0.81 | DRD2 (0.56) | MEN1GAAKMT2AALDH1A1PRMT5 | |
| SCHEMBL21145808 | 0.81 | DRD2 (0.56) | MEN1GAAKMT2AALDH1A1PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026371-A1 | DUAL NAV1.2/5HT2A INHIBITORS FOR TREATING CNS DISORDERS | SUNOVION PHARMACEUTICALS INC. (US) | 2018-02-08 | — | — | WO | disclosed |