SCHEMBL19852643

SCHEMBL19852643

O=C1c2cccc(-n3c4ccccc4c4c(C(F)(F)F)cccc43)c2C(=O)N1c1c(-c2ccccc2)cc(-c2ccccc2)cc1-c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.34
PDE6D O43924 1/20 0.33
GALR3 O60755 1/20 0.33
HTR4 Q13639 1/20 0.33
NR1H2 P55055 1/20 0.33
MAPK14 Q16539 1/20 0.32
ALDH1A1 P00352 2/20 0.31
LDHA P00338 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
S1PR1 P21453 2/20 0.31
S1PR3 Q99500 2/20 0.31
POLB P06746 1/20 0.30
RORC P51449 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19848864 0.94 TYMS (0.36) TYMSPDE6DGALR3HTR4NR1H2
SCHEMBL19848863 0.90 TYMS (0.39) TYMSPDE6DGALR3HTR4NR1H2
SCHEMBL19842449 0.89 TYMS (0.34) TYMSPDE6DGALR3HTR4NR1H2
SCHEMBL19848815 0.89 EDNRB (0.35) TYMSPDE6DGALR3HTR4ALDH1A1
SCHEMBL23516369 0.89 TACR1 (0.34) TYMSPDE6DGALR3HTR4NR1H2
SCHEMBL19850890 0.88 TYMS (0.33) TYMSPDE6DGALR3HTR4NR1H2
SCHEMBL19852639 0.87 PDE6D (0.45) TYMSPDE6DGALR3HTR4NR1H2
SCHEMBL19842369 0.87 TYMS (0.40) TYMSPDE6DNR1H2MAPK14ALDH1A1
SCHEMBL19842459 0.86 TYMS (0.36) TYMSPDE6DGALR3HTR4NR1H2
SCHEMBL19852642 0.85 GALR3 (0.37) TYMSPDE6DGALR3HTR4NR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11276825-B2 Organic molecules for use in organic devices CYNORA GMBH (DE) 2022-03-15 US disclosed
US-20210184134-A1 ORGANIC MOLECULES FOR USE IN ORGANIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2021-06-17 US disclosed
EP-3279193-B1 COMPOUNDS COMPRISING A PHTHALIMIDE GROUP AND CARBAZOLE OR ITS ANALOGUES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-05-08 EP disclosed
WO-2018024723-A1 PHTHALIMIDE AND CARBAZOLE OR ANALOGS THEREOF CONTAINING COMPOUNDS FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210184134-A1 ORGANIC MOLECULES FOR USE IN ORGANIC DEVICES CHRM1, C1S, DNMT3L TYMS 2681/4885PDE6D 611/4885GALR3 367/4885
US-11276825-B2 Organic molecules for use in organic devices AOX1, OR10J3, L1CAM TYMS 1508/4885PDE6D 162/4885GALR3 990/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.