SCHEMBL19852882

SCHEMBL19852882

NC(=O)CC[C@H](N)C(O)N1CCCC2(CCNC2=O)C1

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
OTUD7B Q6GQQ9 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19852885 0.78 OTUD7B (0.36) OTUD7B
SCHEMBL16750021 0.70 OTUD7B (0.46) OTUD7B
SCHEMBL23103171 0.70 OTUD7B (0.46) OTUD7B
SCHEMBL23107538 0.70 OTUD7B (0.46) OTUD7B
SCHEMBL24338486 0.70 OTUD7B (0.36) OTUD7B
SCHEMBL23393644 0.68 OTUD7B (0.44) OTUD7B
SCHEMBL24338426 0.68 OTUD7B (0.39) OTUD7B
SCHEMBL19852879 0.67 OTUD7B (0.38) OTUD7B
SCHEMBL24339020 0.67 OTUD7B (0.38) OTUD7B
SCHEMBL24339056 0.66 OTUD7B (0.42) OTUD7B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018026779-A1 SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF APTINYX INC. (US) 2018-02-08 WO disclosed