Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 10/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 6/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 3/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2772055 | 1.00 | PREP (0.44) | PREPPSMB5CXCR2F2PRSS1 | |
| SCHEMBL2790529 | 0.88 | PREP (0.47) | PREPPSMB5CXCR2F2 | |
| SCHEMBL2788790 | 0.87 | PREP (0.44) | PREPPSMB5CXCR2F2 | |
| SCHEMBL21911818 | 0.86 | PSMB5 (0.39) | PREPPSMB5CXCR2F2PRSS1 | |
| SCHEMBL20571176 | 0.86 | PSMB5 (0.39) | PREPPSMB5CXCR2F2PRSS1 | |
| SCHEMBL23200672 | 0.86 | PSMB5 (0.39) | PREPPSMB5CXCR2F2PRSS1 | |
| SCHEMBL21955866 | 0.86 | PREP (0.38) | PREPPSMB5CXCR2F2PRSS1 | |
| SCHEMBL20571080 | 0.85 | PREP (0.44) | PREPPSMB5CXCR2F2PRSS1 | |
| SCHEMBL21911461 | 0.85 | PREP (0.44) | PREPPSMB5CXCR2F2PRSS1 | |
| SCHEMBL23200757 | 0.84 | PREP (0.44) | PREPPSMB5CXCR2F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11560392-B2 | Boron-containing compounds | VenatoRx Pharmaceuticals, Inc. (US) | 2023-01-24 | — | — | US | disclosed |
| EP-3494121-B1 | BORON-CONTAINING COMPOUNDS | VENATORX PHARMACEUTICALS INC (US) | 2021-10-06 | — | — | EP | disclosed |
| US-20210163506-A1 | BORON-CONTAINING COMPOUNDS | SNAPDRAGON CHEMISTRY, INC. | 2021-06-03 | — | — | US | disclosed |
| US-10889600-B2 | Boron-containing compounds | VenatoRx Pharmaceuticals, Inc. (US) | 2021-01-12 | — | — | US | disclosed |
| US-20200181174-A1 | BORON-CONTAINING COMPOUNDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-06-11 | — | — | US | disclosed |
| WO-2018027062-A1 | BORON-CONTAINING COMPOUNDS | VenatoRx Pharmaceuticals, Inc. (US) | 2018-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11560392-B2 | Boron-containing compounds | BCL6B, BCL6, BCCIP | PREP 2538/4885PSMB5 2347/4885CXCR2 557/4885 |
| US-10889600-B2 | Boron-containing compounds | BCL6B, BCL6, BCCIP | PREP 2538/4885PSMB5 2347/4885CXCR2 557/4885 |
| US-20200181174-A1 | BORON-CONTAINING COMPOUNDS | BCL6B, BCL6, BCCIP | PREP 2538/4885PSMB5 2347/4885CXCR2 557/4885 |
| US-20210163506-A1 | BORON-CONTAINING COMPOUNDS | BCL6B, BCL6, BCCIP | PREP 2538/4885PSMB5 2347/4885CXCR2 557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.