Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 10/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 4/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20571080 | 1.00 | PREP (0.44) | PREPPSMB5CXCR2F2PRSS1 | |
| SCHEMBL17337120 | 0.92 | PREP (0.44) | PREPPSMB5CXCR2F2PRSS1 | |
| SCHEMBL23414423 | 0.92 | PREP (0.44) | PREPPSMB5CXCR2F2PRSS1 | |
| SCHEMBL23200757 | 0.92 | PREP (0.44) | PREPPSMB5CXCR2F2PRSS1 | |
| SCHEMBL23200703 | 0.91 | PSMB5 (0.39) | PREPPSMB5CXCR2F2PRSS1 | |
| SCHEMBL23200947 | 0.90 | PREP (0.40) | PREPPSMB5CXCR2F2PRSS1 | |
| SCHEMBL23413644 | 0.89 | PSMB5 (0.46) | PREPPSMB5CXCR2F2PRSS1 | |
| SCHEMBL21911590 | 0.86 | PREP (0.39) | PREPPSMB5CXCR2F2PRSS1 | |
| SCHEMBL23200663 | 0.85 | PREP (0.40) | PREPPSMB5CXCR2F2PRSS1 | |
| SCHEMBL2772055 | 0.85 | PREP (0.44) | PREPPSMB5CXCR2F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200102331-A1 | PENICILLIN-BINDING PROTEIN INHIBITORS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200102331-A1 | PENICILLIN-BINDING PROTEIN INHIBITORS | PEPD, BPGM, EBPL | PREP 6/4885PSMB5 1371/4885CXCR2 2165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.