SCHEMBL19853470

SCHEMBL19853470

CCN1C(=O)NC(C)(CC)C1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 3/20 0.47
POLB P06746 2/20 0.43
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
F2 P00734 1/20 0.39
ELANE P08246 1/20 0.39
CTSG P08311 1/20 0.39
CTRC Q99895 1/20 0.39
ATM Q13315 1/20 0.37
KMT2A Q03164 2/20 0.37
ALDH1A1 P00352 4/20 0.37
KDM4E B2RXH2 3/20 0.37
MAPT P10636 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
LMNA P02545 2/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20614629 1.00 FPR2 (0.47) FPR2POLBNPC1RAB9AF2
SCHEMBL24828775 0.83 ATM (0.42) FPR2POLBF2ELANECTSG
SCHEMBL9179767 0.83 FPR2 (0.48) FPR2POLBNPC1RAB9AATM
SCHEMBL1364096 0.83 POLB (0.41) FPR2POLBF2ELANECTSG
SCHEMBL11750459 0.80 FPR2 (0.43) FPR2POLBNPC1RAB9AATM
SCHEMBL15621432 0.80 FPR2 (0.43) FPR2POLBNPC1RAB9AATM
SCHEMBL23130049 0.80 FPR2 (0.43) FPR2POLBNPC1RAB9AATM
SCHEMBL5148354 0.80 FPR2 (0.43) FPR2POLBNPC1RAB9AATM
SCHEMBL15427233 0.79 FPR2 (0.42) FPR2POLBNPC1RAB9AATM
SCHEMBL26948732 0.79 POLB (0.50) FPR2POLBNPC1RAB9AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180036308-A1 NOVEL COMPOUNDS AUTIFONY SRL (IT) 2018-02-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180036308-A1 NOVEL COMPOUNDS CYFIP1, CYFIP2, ZFX FPR2 1811/4885POLB 1145/4885NPC1 1685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.