⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19846881 | 0.80 | MEN1 (0.32) | — | |
| SCHEMBL11477583 | 0.78 | — | — | |
| SCHEMBL10144671 | 0.78 | — | — | |
| SCHEMBL14344763 | 0.78 | — | — | |
| SCHEMBL11484387 | 0.77 | DNM1 (0.39) | — | |
| SCHEMBL9353823 | 0.77 | — | — | |
| SCHEMBL12132034 | 0.75 | — | — | |
| SCHEMBL11192774 | 0.75 | — | — | |
| SCHEMBL11476583 | 0.72 | HRH4 (0.54) | — | |
| SCHEMBL13348741 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10179124-B2 | Benzamides and related inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2019-01-15 | — | — | US | disclosed |
| US-20180036296-A1 | BENZAMIDES AND RELATED INHIBITORS OF FACTOR XA | COR THERAPEUTICS, INC. | 2018-02-08 | — | — | US | disclosed |