Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19853740 | 0.93 | BCL2 (0.69) | BCL2 | |
| SCHEMBL19853626 | 0.93 | BCL2 (0.69) | BCL2 | |
| SCHEMBL21573186 | 0.91 | BCL2 (0.70) | BCL2 | |
| SCHEMBL22562897 | 0.90 | BCL2 (0.69) | BCL2 | |
| SCHEMBL21573183 | 0.90 | BCL2 (0.69) | BCL2 | |
| SCHEMBL22562894 | 0.90 | BCL2 (0.69) | BCL2 | |
| SCHEMBL29376071 | 0.90 | BCL2 (0.83) | BCL2 | |
| SCHEMBL19839955 | 0.90 | BCL2 (0.83) | BCL2 | |
| SCHEMBL23865993 | 0.90 | BCL2 (0.75) | BCL2 | |
| SCHEMBL24520027 | 0.90 | BCL2 (0.69) | BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018027097-A1 | N-(PHENYLSULFONYL)BENZAMIDES AND RELATED COMPOUNDS AS BCL-2 INHIBITORS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2018-02-08 | — | — | WO | disclosed |