SCHEMBL19853829

SCHEMBL19853829

C=CCCC1CCC(c2ccc(C3CCC(C4CCC(OCCN(C)C(=O)C(=C)C)CC4)CC3)c(F)c2)CC1

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 2/20 0.33
▸ OPRL1 P41146 3/20 0.32
▸ HCRTR2 O43614 2/20 0.32
▸ ABCB11 O95342 1/20 0.31
▸ EGFR P00533 1/20 0.31
▸ ERBB2 P04626 1/20 0.31
▸ TEC P42680 1/20 0.31
▸ TXK P42681 1/20 0.31
▸ BLK P51451 1/20 0.31
▸ BMX P51813 1/20 0.31
▸ JAK3 P52333 1/20 0.31
▸ BTK Q06187 1/20 0.31
▸ ITK Q08881 1/20 0.31
▸ KCNH2 Q12809 1/20 0.31
▸ ERBB4 Q15303 1/20 0.31
▸ PI4KB Q9UBF8 1/20 0.31
▸ FFAR4 Q5NUL3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19853839 0.90 BTK (0.39) GPR119OPRL1HCRTR2ABCB11EGFR
SCHEMBL19854096 0.89 GPR119 (0.34) GPR119OPRL1HCRTR2BTKKCNH2
SCHEMBL19854007 0.85 OPRL1 (0.36) GPR119OPRL1HCRTR2ITK
SCHEMBL19854118 0.84 OPRL1 (0.35) OPRL1
SCHEMBL21321654 0.82 OPRL1 (0.37) GPR119OPRL1HCRTR2FFAR4
SCHEMBL19854115 0.81 BTK (0.38) GPR119OPRL1HCRTR2ABCB11EGFR
SCHEMBL19722378 0.80 FFAR4 (0.33) GPR119OPRL1FFAR4
SCHEMBL19854017 0.80 ITK (0.39) GPR119OPRL1HCRTR2BTKITK
SCHEMBL19853830 0.80 OPRL1 (0.35) OPRL1
SCHEMBL19853834 0.80 OPRL1 (0.35) OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 — — US disclosed
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed
WO-2018025974-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND DISPLAY DEVICE JNC株式会社 2018-02-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE SP1, MBD2, PAXBP1 GPR119 2681/4885OPRL1 3416/4885HCRTR2 2753/4885
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device SP1, MBD2, PAXBP1 GPR119 2681/4885OPRL1 3416/4885HCRTR2 2753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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