SCHEMBL19853983

SCHEMBL19853983

C=CC(=O)NC1CCC(CCCCCCC)CC1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ ZDHHC20 Q5W0Z9 1/20 0.46
▸ ZDHHC2 Q9UIJ5 1/20 0.46
▸ TP53 P04637 1/20 0.43
▸ MEN1 O00255 2/20 0.42
▸ KMT2A Q03164 2/20 0.42
▸ HTT P42858 1/20 0.42
▸ EPHX1 P07099 10/20 0.41
▸ CYP1A2 P05177 1/20 0.41
▸ CYP2D6 P10635 1/20 0.41
▸ CYP2C9 P11712 1/20 0.41
▸ CYP2C19 P33261 1/20 0.41
▸ ALDH1A1 P00352 1/20 0.40
▸ MAPT P10636 1/20 0.40
▸ HPGD P15428 1/20 0.40
▸ EPHX2 P34913 2/20 0.40
▸ PKM P14618 1/20 0.40
▸ SMYD3 Q9H7B4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19854563 0.97 ZDHHC20 (0.42) ZDHHC20ZDHHC2TP53MEN1KMT2A
SCHEMBL19855974 0.96 ZDHHC20 (0.43) ZDHHC20ZDHHC2TP53MEN1KMT2A
SCHEMBL19855979 0.94 ZDHHC20 (0.41) ZDHHC20ZDHHC2TP53MEN1KMT2A
SCHEMBL20370536 0.94 ZDHHC20 (0.41) ZDHHC20ZDHHC2TP53MEN1KMT2A
SCHEMBL19856072 0.94 ZDHHC20 (0.41) ZDHHC20ZDHHC2TP53MEN1KMT2A
SCHEMBL19854396 0.93 ZDHHC20 (0.40) ZDHHC20ZDHHC2TP53MEN1KMT2A
SCHEMBL19853809 0.93 ZDHHC20 (0.40) ZDHHC20ZDHHC2TP53MEN1KMT2A
SCHEMBL19854554 0.92 ZDHHC20 (0.39) ZDHHC20ZDHHC2TP53MEN1KMT2A
SCHEMBL19853802 0.90 ZDHHC20 (0.38) ZDHHC20ZDHHC2TP53MEN1KMT2A
SCHEMBL19854401 0.88 ZDHHC20 (0.36) ZDHHC20ZDHHC2TP53MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 — — US disclosed
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed
WO-2018025974-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND DISPLAY DEVICE JNC株式会社 2018-02-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE SP1, MBD2, PAXBP1 ZDHHC20 946/4885ZDHHC2 1841/4885TP53 1638/4885
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device SP1, MBD2, PAXBP1 ZDHHC20 946/4885ZDHHC2 1841/4885TP53 1638/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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