SCHEMBL19854601

SCHEMBL19854601

C=CC(=O)NCCCc1ccc(-c2ccc(-c3ccc(CCCCC)cc3)cc2F)cc1

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ RARB P10826 10/20 0.56
▸ RARA P10276 2/20 0.53
▸ RARG P13631 1/20 0.53
▸ THRB P10828 6/20 0.49
▸ THRA P10827 5/20 0.49
▸ ZDHHC20 Q5W0Z9 1/20 0.46
▸ ZDHHC2 Q9UIJ5 1/20 0.46
▸ GAA P10253 1/20 0.44
▸ MEN1 O00255 2/20 0.43
▸ KMT2A Q03164 2/20 0.43
▸ TGM2 P21980 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.41
▸ MAPT P10636 1/20 0.41
▸ MTOR P42345 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19854600 0.96 RARB (0.56) RARBRARARARGTHRBTHRA
SCHEMBL19854616 0.96 RARB (0.56) RARBRARARARGTHRBTHRA
SCHEMBL19854610 0.94 RARB (0.49) RARBRARARARGTHRBTHRA
SCHEMBL19855127 0.91 RARB (0.50) RARBRARARARGTHRBTHRA
SCHEMBL19854609 0.89 RARB (0.49) RARBRARARARGTHRBTHRA
SCHEMBL19854607 0.89 RARB (0.49) RARBRARARARGTHRBTHRA
SCHEMBL19854605 0.89 THRB (0.53) RARBRARARARGTHRBTHRA
SCHEMBL19855134 0.88 RARB (0.48) RARBRARARARGTHRBTHRA
SCHEMBL19854606 0.88 GAA (0.42) RARBRARARARGTHRBTHRA
SCHEMBL19854615 0.88 RARB (0.55) RARBRARARARGTHRBTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 — — US disclosed
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed
WO-2018025974-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND DISPLAY DEVICE JNC株式会社 2018-02-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE SP1, MBD2, PAXBP1 RARB 1437/4885RARA 1599/4885RARG 598/4885
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device SP1, MBD2, PAXBP1 RARB 1437/4885RARA 1599/4885RARG 598/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback