SCHEMBL19854970

SCHEMBL19854970

C=C(C)C(=O)Nc1ccc(-c2ccc(C3CCC(CCCCC)CC3)cc2)c(CC)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ CYP2C9 P11712 1/20 0.38
▸ MAPK14 Q16539 6/20 0.36
▸ MEN1 O00255 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ POLB P06746 2/20 0.34
▸ RECQL P46063 2/20 0.34
▸ BLM P54132 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ BAZ1A Q9NRL2 1/20 0.34
▸ DGAT1 O75907 3/20 0.33
▸ TDP1 Q9NUW8 2/20 0.33
▸ SOAT1 P35610 1/20 0.33
▸ IMPDH2 P12268 1/20 0.33
▸ IMPDH1 P20839 1/20 0.33
▸ APAF1 O14727 1/20 0.33
▸ GRK2 P25098 1/20 0.33
▸ APEX1 P27695 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19854971 0.99 MAPT (0.38) MAPTALDH1A1LMNACYP2C9MAPK14
SCHEMBL19856055 0.88 MAPT (0.44) MAPTALDH1A1LMNACYP2C9MEN1
SCHEMBL19855139 0.87 MAPT (0.44) MAPTALDH1A1LMNACYP2C9MEN1
SCHEMBL19854187 0.87 MAPT (0.44) MAPTALDH1A1LMNACYP2C9MEN1
SCHEMBL20370415 0.87 MAPT (0.47) MAPTALDH1A1LMNACYP2C9MEN1
SCHEMBL20370468 0.86 THRA (0.42) MAPTALDH1A1LMNACYP2C9MAPK14
SCHEMBL20370469 0.86 THRA (0.43) MAPTALDH1A1LMNACYP2C9MAPK14
SCHEMBL19854507 0.86 MAPT (0.46) MAPTALDH1A1LMNACYP2C9MEN1
SCHEMBL19856067 0.84 MAPT (0.44) MAPTALDH1A1LMNACYP2C9MEN1
SCHEMBL19854951 0.83 SPHK1 (0.40) MAPTALDH1A1LMNACYP2C9KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 — — US disclosed
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed
WO-2018025974-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND DISPLAY DEVICE JNC株式会社 2018-02-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE SP1, MBD2, PAXBP1 MAPT 1073/4885ALDH1A1 3826/4885LMNA 1840/4885
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device SP1, MBD2, PAXBP1 MAPT 1073/4885ALDH1A1 3826/4885LMNA 1840/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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