⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15390690 | 0.97 | USP2 (0.39) | — | |
| SCHEMBL5037562 | 0.93 | INMT (0.40) | — | |
| SCHEMBL1826475 | 0.93 | INMT (0.40) | — | |
| SCHEMBL22721043 | 0.93 | — | — | |
| SCHEMBL206437 | 0.90 | USP2 (0.44) | — | |
| SCHEMBL17317854 | 0.90 | — | — | |
| SCHEMBL6600866 | 0.90 | USP2 (0.44) | — | |
| SCHEMBL1828720 | 0.90 | USP2 (0.44) | — | |
| SCHEMBL1824179 | 0.90 | USP2 (0.44) | — | |
| SCHEMBL204533 | 0.90 | USP2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116640157-A | METTL3 inhibitor and composition thereof and application of METTL3 inhibitor and composition thereof in medicine | 海思科医药集团股份有限公司 | 2023-08-25 | — | — | CN | claimed |
| EP-3626239-B1 | EZH2 INHIBITOR COMBINED WITH BTK INHIBITOR FOR TREATING TUMOR | JIANGSU HENGRUI PHARMACEUTICALS CO LTD (CN) | 2024-07-03 | — | — | EP | disclosed |
| US-20240101566-A1 | TRICYCLIC UBIQUITIN SPECIFIC PROTEASE 1 INHIBITOR AND USE THEREOF | Xuanzhu Biopharmaceutical Co., Ltd. (CN) | 2024-03-28 | — | — | US | disclosed |
| EP-4335852-A1 | TRICYCLIC UBIQUITIN SPECIFIC PROTEASE 1 INHIBITOR AND USE THEREOF | Shandong Xuanzhu Pharma Co., Ltd. (CN) | 2024-03-13 | — | — | EP | disclosed |
| CN-116640157-A | METTL3 inhibitor and composition thereof and application of METTL3 inhibitor and composition thereof in medicine | 海思科医药集团股份有限公司 | 2023-08-25 | — | — | CN | disclosed |
| US-20230219925-A1 | BENZO FIVE-MEMBERED NITROGEN HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Guangzhou Institutes of Biomedicine and Health Chinese Academy of Sciences (CN) | 2023-07-13 | — | — | US | disclosed |
| WO-2023109521-A1 | PARP INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 凯复(苏州)生物医药有限公司 | 2023-06-22 | — | — | WO | disclosed |
| WO-2023098825-A1 | SOS1 INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 勤浩医药（苏州）有限公司 | 2023-06-08 | — | — | WO | disclosed |
| EP-3919484-B1 | HEXONE GLUCOKINASE INHIBITOR AND USE THEREOF | SHANDONG XUANZHU PHARMA CO LTD (CN) | 2023-05-24 | — | — | EP | disclosed |
| CN-109568323-B | Antibacterial composition and use thereof | 吉林四环制药有限公司 | 2022-09-30 | — | — | CN | disclosed |
| WO-2020156445-A1 | HEXONE GLUCOKINASE INHIBITOR AND USE THEREOF | 山东轩竹医药科技有限公司 | 2020-08-06 | — | — | WO | disclosed |
| CN-111171049-A | Tyrosine kinase inhibitors and uses thereof | 山东轩竹医药科技有限公司 | 2020-05-19 | — | — | CN | disclosed |
| EP-3626239-A1 | USE OF EZH2 INHIBITOR COMBINED WITH BTK INHIBITOR IN PREPARING DRUG FOR TREATING TUMOR | Jiangsu Hengrui Medicine Co., Ltd. (CN) | 2020-03-25 | — | — | EP | disclosed |
| WO-2019214546-A1 | FUSED RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 (CN) | 2019-11-14 | — | — | WO | disclosed |
| WO-2019179369-A1 | RING-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR, AND MEDICAL APPLICATION THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-09-26 | — | — | WO | disclosed |
| WO-2019179362-A1 | AMIDINE AND GUANIDINE DERIVATIVES, PREPARATION METHOD THEREFOR AND MEDICAL USES THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-09-26 | — | — | WO | disclosed |
| WO-2019141096-A1 | SUBSTITUTED UREA COMPOUND AND PREPARATION METHOD AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-07-25 | — | — | WO | disclosed |
| US-10167283-B2 | β-lactamase inhibitors and uses thereof | SUANZHU PHARMA CO., LTD. (CN) | 2019-01-01 | — | — | US | disclosed |
| US-20180148448-A1 | ß-LACTAMASE INHIBITORS AND USES THEREOF | Xuanzhu Pharma Co., Ltd. (CN) | 2018-05-31 | — | — | US | disclosed |
| EP-3281942-A1 | B-LACTAMASE INHIBITOR AND APPLICATION THEREOF | Xuanzhu Pharma Co., Ltd. (CN) | 2018-02-14 | — | — | EP | disclosed |