SCHEMBL19856488

SCHEMBL19856488

C=Cc1ccc(-c2c[c]ccc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
TSHR P16473 1/20 0.39
POLB P06746 1/20 0.32
DAPK3 O43293 1/20 0.32
JAK2 O60674 1/20 0.32
ABL1 P00519 1/20 0.32
NTRK1 P04629 1/20 0.32
FYN P06241 1/20 0.32
CSF1R P07333 1/20 0.32
RET P07949 1/20 0.32
MET P08581 1/20 0.32
PDGFRB P09619 1/20 0.32
FGFR1 P11362 1/20 0.32
FLT3 P36888 1/20 0.32
MAPK8 P45983 1/20 0.32
GSK3B P49841 1/20 0.32
CDK9 P50750 1/20 0.32
RPS6KA3 P51812 1/20 0.32
LIMK1 P53667 1/20 0.32
MAP2K1 Q02750 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17200847 0.82 ALDH1A1 (0.37) ALDH1A1TDP1
SCHEMBL24983 0.78 ALDH1A1 (0.47) ALDH1A1TSHRTDP1
SCHEMBL2448213 0.78 ALDH1A1 (0.47) ALDH1A1TSHRTDP1
SCHEMBL1510123 0.78 ALDH1A1 (0.37) ALDH1A1
Water SCHEMBL7178879 0.78 ALDH1A1 (0.73) ALDH1A1TSHRPOLBDAPK3JAK2
SCHEMBL610112 0.78 ALDH1A1 (0.33) ALDH1A1
SCHEMBL247802 0.76
SCHEMBL6317768 0.76 ALDH1A1 (0.55) ALDH1A1TSHRDAPK3JAK2ABL1
SCHEMBL447854 0.75 ALDH1A1 (0.68) ALDH1A1TSHRPOLBTDP1HDAC2
SCHEMBL2997715 0.75 ALDH1A1 (0.68) ALDH1A1TSHRPOLBTDP1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3617758-B1 COMPOSITION FOR FORMING OPTICAL WAVEGUIDE WHICH CONTAINS REACTIVE SILSESQUIOXANE COMPOUND NISSAN CHEMICAL CORP (JP) 2023-08-09 EP disclosed
US-11333800-B2 Optical waveguide-forming composition which contains reactive silsesquioxane compound NISSAN CHEMICAL CORPORATION (JP) 2022-05-17 US disclosed
US-10899891-B2 Reactive polysiloxane and polymerizable composition comprising same NISSAN CHEMICAL CORPORATION (JP) 2021-01-26 US disclosed
US-10894800-B2 Polymerizable silane compound NISSAN CHEMICAL CORPORATION (JP) 2021-01-19 US disclosed
EP-3466956-B1 POLYMERIZABLE SILANE COMPOUND NISSAN CHEMICAL CORP (JP) 2020-12-09 EP disclosed
US-10787535-B2 Polymerizable composition containing reactive silsesquioxane compound containing phenanthrene ring NISSAN CHEMICAL CORPORATION (JP) 2020-09-29 US disclosed
EP-3466994-B1 REACTIVE POLYSILOXANE AND POLYMERIZABLE COMPOSITION CONTAINING SAME NISSAN CHEMICAL CORP (JP) 2020-09-16 EP disclosed
US-20200148875-A1 OPTICAL WAVEGUIDE-FORMING COMPOSITION WHICH CONTAINS REACTIVE SILSESQUIOXANE COMPOUND NISSAN CHEMICAL CORPORATION (JP) 2020-05-14 US disclosed
EP-3373051-B1 COMPOSITION FOR FORMING OPTICAL WAVEGUIDE NISSAN CHEMICAL CORP (JP) 2020-03-11 EP disclosed
EP-3617758-A1 COMPOSITION FOR FORMING OPTICAL WAVEGUIDE WHICH CONTAINS REACTIVE SILSESQUIOXANE COMPOUND Nissan Chemical Corporation (JP) 2020-03-04 EP disclosed
EP-3327049-B1 REACTIVE SILSESQUIOXANE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING AROMATIC VINYL COMPOUND NISSAN CHEMICAL CORP (JP) 2019-05-29 EP disclosed
EP-3466994-A1 REACTIVE POLYSILOXANE AND POLYMERIZABLE COMPOSITION CONTAINING SAME Nissan Chemical Corporation (JP) 2019-04-10 EP disclosed
US-10253126-B2 Optical waveguide-forming composition NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2019-04-09 US disclosed
EP-3444284-A1 POLYMERIZABLE COMPOSITION CONTAINING REACTIVE SILSESQUIOXANE COMPOUND CONTAINING PHENANTHRENE RING Nissan Chemical Corporation (JP) 2019-02-20 EP disclosed
US-20180305488-A1 OPTICAL WAVEGUIDE-FORMING COMPOSITION NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-10-25 US disclosed
EP-3373051-A1 COMPOSITION FOR FORMING OPTICAL WAVEGUIDE Nissan Chemical Industries, Ltd. (JP) 2018-09-12 EP disclosed
EP-3367144-A1 MANUFACTURING METHOD FOR GI OPTICAL WAVEGUIDE Nissan Chemical Industries, Ltd. (JP) 2018-08-29 EP disclosed
EP-3327049-A1 REACTIVE SILSESQUIOXANE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING AROMATIC VINYL COMPOUND Nissan Chemical Industries, Ltd. (JP) 2018-05-30 EP disclosed
US-20180079849-A1 POLYMERIZABLE RESIN COMPOSITION CONTAINING REACTIVE SILSESQUIOXANE COMPOUND NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-03-22 US disclosed
EP-3281959-A1 POLYMERIZABLE RESIN COMPOSITION CONTAINING REACTIVE SILSESQUIOXANE COMPOUND Nissan Chemical Industries, Ltd. (JP) 2018-02-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10894800-B2 Polymerizable silane compound PCNA, ARL1, CCNE1 ALDH1A1 958/4885TSHR 4498/4885POLB 1336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.