Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19857014 | 0.94 | TAS1R3 (0.45) | TAS1R3TAS1R1PYGLPDE10ACTNNB1 | |
| SCHEMBL7942843 | 0.94 | TAS1R3 (0.41) | TAS1R3TAS1R1PDE10A | |
| SCHEMBL1549546 | 0.94 | TAS1R3 (0.45) | TAS1R3TAS1R1PYGLPDE10ACTNNB1 | |
| SCHEMBL1550088 | 0.94 | TAS1R3 (0.41) | TAS1R3TAS1R1PDE10A | |
| SCHEMBL1549475 | 0.88 | TAS1R3 (0.52) | TAS1R3TAS1R1PYGL | |
| SCHEMBL1550350 | 0.87 | CYP51A1 (0.46) | TAS1R3TAS1R1PYGLCTNNB1 | |
| SCHEMBL1549856 | 0.87 | ALB (0.43) | TAS1R3TAS1R1 | |
| SCHEMBL1550136 | 0.87 | TAS1R3 (0.42) | TAS1R3TAS1R1PDE10A | |
| SCHEMBL7940976 | 0.87 | TAS1R3 (0.42) | TAS1R3TAS1R1PDE10A | |
| SCHEMBL1549857 | 0.85 | TAS1R3 (0.47) | TAS1R3TAS1R1PYGLPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925857-B1 | USE OF TRPV4 ANTAGONISTS TO AMELIORATE HYDROCEPHALUS AND RELATED MATERIALS AND METHODS | UNIV INDIANA RES & TECH CORP (US) | 2018-02-14 | — | — | EP | claimed |