Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15537387 | 0.93 | MAPT (0.33) | MAPTCACNA1BAPBA1CYP3A4CYP2C9 | |
| SCHEMBL19856888 | 0.86 | — | — | |
| SCHEMBL15537452 | 0.84 | — | — | |
| SCHEMBL17910000 | 0.84 | — | — | |
| SCHEMBL17909982 | 0.81 | CTSK (0.32) | — | |
| SCHEMBL17909978 | 0.81 | CTSK (0.32) | — | |
| SCHEMBL17909979 | 0.78 | — | — | |
| SCHEMBL17910023 | 0.76 | — | — | |
| SCHEMBL19932590 | 0.76 | — | — | |
| SCHEMBL17910020 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855508-B1 | CYCLOSPORIN A ANALOGS | ALLERGAN INC (US) | 2018-02-14 | — | — | EP | disclosed |