Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.43 |
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | CCKBR | P32239 | 3/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19856894 | 1.00 | DRD2 (0.45) | DRD2CYP51A1STAT6HRH4EGFR | |
| SCHEMBL19856921 | 0.95 | CYP51A1 (0.43) | DRD2CYP51A1STAT6HRH4EGFR | |
| SCHEMBL19856919 | 0.95 | CYP51A1 (0.43) | DRD2CYP51A1STAT6HRH4EGFR | |
| SCHEMBL19856881 | 0.94 | DRD2 (0.43) | DRD2CYP51A1STAT6HRH4EGFR | |
| SCHEMBL19856870 | 0.94 | DRD2 (0.43) | DRD2CYP51A1STAT6HRH4EGFR | |
| SCHEMBL19856879 | 0.94 | DRD2 (0.43) | DRD2CYP51A1STAT6HRH4EGFR | |
| SCHEMBL19856869 | 0.94 | DRD2 (0.43) | DRD2CYP51A1STAT6HRH4EGFR | |
| SCHEMBL1931303 | 0.93 | DRD2 (0.47) | DRD2CYP51A1STAT6HRH4PYGL | |
| SCHEMBL1931738 | 0.93 | DRD2 (0.47) | DRD2CYP51A1STAT6HRH4PYGL | |
| SCHEMBL1931683 | 0.93 | DRD2 (0.47) | DRD2CYP51A1STAT6HRH4PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925857-B1 | USE OF TRPV4 ANTAGONISTS TO AMELIORATE HYDROCEPHALUS AND RELATED MATERIALS AND METHODS | UNIV INDIANA RES & TECH CORP (US) | 2018-02-14 | — | — | EP | claimed |