Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 4/20 | 0.35 |
| ▸ | DRD3 | P35462 | 4/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | STAT6 | P42226 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | TEK | Q02763 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.34 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.34 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.34 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.34 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1549343 | 1.00 | HTR2C (0.37) | HTR2CDRD4DRD3HTR1ADRD2 | |
| SCHEMBL1549685 | 0.93 | ABCB1 (0.38) | DRD4DRD3HTR1ADRD2HTR2A | |
| SCHEMBL1550720 | 0.92 | TRPV1 (0.37) | HTR2CDRD2STAT6HSPA5HSPA8 | |
| SCHEMBL1550596 | 0.91 | NTRK1 (0.39) | DRD2STAT6HSPA5HSPA8HSPA9 | |
| SCHEMBL1549968 | 0.91 | NTRK1 (0.35) | HTR2CDRD2STAT6TAS1R3TAS1R1 | |
| SCHEMBL16456898 | 0.89 | DRD2 (0.38) | HTR2CDRD2STAT6TAS1R3TAS1R1 | |
| SCHEMBL1550494 | 0.89 | DRD2 (0.38) | HTR2CDRD2STAT6TAS1R3TAS1R1 | |
| SCHEMBL1550985 | 0.88 | NTRK1 (0.37) | DRD2STAT6HSPA5HSPA8HSPA9 | |
| SCHEMBL1550758 | 0.88 | NAMPT (0.40) | DRD3DRD2STAT6TAS1R3TAS1R1 | |
| SCHEMBL1550050 | 0.88 | CYP51A1 (0.40) | DRD2STAT6TAS1R3TAS1R1HSPA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925857-B1 | USE OF TRPV4 ANTAGONISTS TO AMELIORATE HYDROCEPHALUS AND RELATED MATERIALS AND METHODS | UNIV INDIANA RES & TECH CORP (US) | 2018-02-14 | — | — | EP | claimed |