Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24262370 | 0.83 | — | — | |
| SCHEMBL9743398 | 0.82 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL1935146 | 0.80 | SLC1A3 (0.31) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1305300 | 0.79 | SLC1A2 (0.35) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL19858945 | 0.79 | MEN1 (0.39) | — | |
| SCHEMBL26908708 | 0.79 | — | — | |
| SCHEMBL9018972 | 0.76 | NPC1 (0.42) | NPC1 | |
| SCHEMBL15280 | 0.76 | RNPEP (0.44) | SLC1A3SLC1A2 | |
| SCHEMBL3402119 | 0.72 | SLC1A3 (0.33) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10511072 | 0.72 | SLC1A1 (0.37) | NPC1SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3472169-B1 | METHOD OF MANUFACTURING 4-CHLORO-7H-PYRROLO[2,3-d]PYRIMIDINE | SIEGFRIED NANTONG PHARMACEUTICALS CO LTD (CN) | 2023-04-19 | — | — | EP | claimed |
| EP-3472169-A1 | METHOD OF MANUFACTURING 4-CHLORO-7H-PYRROLO[2,3-d]PYRIMIDINE | Siegfried (Nantong) Pharmaceuticals Co. Ltd. (CN) | 2019-04-24 | — | — | EP | disclosed |
| WO-2018029641-A1 | METHOD OF MANUFACTURING 4-CHLORO-7H-PYRROLO[2,3-d]PYRIMIDINE | SIEGFRIED (NANTONG) PHARMACEUTICALS CO. LTD. (CN) | 2018-02-15 | — | — | WO | disclosed |