SCHEMBL1305300

SCHEMBL1305300

N#CC(CC(C#N)C(=O)O)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC1A2 P43004 3/20 0.35
OR51E2 Q9H255 1/20 0.35
SLC1A3 P43003 2/20 0.31
SLC1A1 P43005 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15280 0.85 RNPEP (0.44) SLC1A2SLC1A3
SCHEMBL3402119 0.81 SLC1A3 (0.33) SLC1A2SLC1A3SLC1A1
SCHEMBL15263375 0.80
SCHEMBL474799 0.79 RNPEP (0.31)
SCHEMBL865611 0.79 RNPEP (0.31)
SCHEMBL19858951 0.79 NPC1 (0.30) SLC1A2SLC1A3SLC1A1
SCHEMBL537504 0.78 TDP1 (0.43) OR51E2
SCHEMBL2146574 0.78
SCHEMBL29956584 0.78
Ammonia Solution, Strong SCHEMBL28482485 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0124755-B1 PROCESS FOR THE MANUFACTURE OF 2-CYANOACRYLATES FROM 2,4-DICYANOGLUTARATES Henkel Kommanditgesellschaft auf Aktien (DE) 1986-07-16 EP claimed
US-4587059-A Process for production of 2-cyanoacrylates from 2,4-dicyanoglutarates HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1986-05-06 US claimed
EP-0124755-A2 Process for the manufacture of 2-cyanoacrylates from 2,4-dicyanoglutarates Henkel Kommanditgesellschaft auf Aktien (DE) 1984-11-14 EP claimed
EP-3558934-B1 PROCESS FOR PREPARING ELECTRON DEFICIENT OLEFINS HENKEL AG & CO KGAA (DE) 2025-04-30 EP disclosed
EP-3558935-B1 PROCESS FOR PREPARING ELECTRON DEFICIENT OLEFINS HENKEL AG & CO KGAA (DE) 2023-11-29 EP disclosed
CN-110114337-B Method for preparing electron-deficient olefins 汉高股份有限及两合公司 2023-05-30 CN disclosed
CN-110121494-B Method for producing cyanoacrylic esters 汉高股份有限及两合公司 2023-02-17 CN disclosed
EP-3558937-B1 PROCESS FOR PREPARING ELECTRON DEFICIENT OLEFINS Henkel IP & Holding GmbH (DE) 2022-05-11 EP disclosed
US-10927071-B2 Process for preparing electron deficient olefins Henkel IP & Holding GmbH (DE) 2021-02-23 US disclosed
US-10913707-B2 Process for preparing electron deficient olefins Henkel IP & Holding GmbH (DE) 2021-02-09 US disclosed
US-10889542-B2 Process for preparing electron deficient olefins Henkel IP & Holding GmbH (DE) 2021-01-12 US disclosed
WO-2009053484-A2 ELECTRON DEFICIENT OLEFINS AND CURABLE COMPOSITIONS PREPARED THEREFROM LOCTITE (R & D) LIMITED (IE) 2009-04-30 WO disclosed
WO-2009053483-A1 ADHESIVE SYSTEMS USING IMINES AND SALTS THEREOF, PRECURSORS TO ELECTRON DEFICIENT OLEFINS AND COREACTANTS THEREFOR LOCTITE (R & D) LIMITED (IE) 2009-04-30 WO disclosed
WO-2008050313-A1 IMINIUM SALTS AND METHODS OF PREPARING ELECTRON DEFICIENT OLEFINS USING SUCH NOVEL IMINIUM SALTS LOCTITE (R & D) LIMITED (IE) 2008-05-02 WO disclosed
EP-0124755-B1 PROCESS FOR THE MANUFACTURE OF 2-CYANOACRYLATES FROM 2,4-DICYANOGLUTARATES Henkel Kommanditgesellschaft auf Aktien (DE) 1986-07-16 EP disclosed
US-4587059-A Process for production of 2-cyanoacrylates from 2,4-dicyanoglutarates HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1986-05-06 US disclosed
US-4587059-A Process for production of 2-cyanoacrylates from 2,4-dicyanoglutarates HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1986-05-06 US disclosed
EP-0124755-A2 Process for the manufacture of 2-cyanoacrylates from 2,4-dicyanoglutarates Henkel Kommanditgesellschaft auf Aktien (DE) 1984-11-14 EP disclosed
EP-0124755-A2 Process for the manufacture of 2-cyanoacrylates from 2,4-dicyanoglutarates Henkel Kommanditgesellschaft auf Aktien (DE) 1984-11-14 EP disclosed
EP-0124755-A2 Process for the manufacture of 2-cyanoacrylates from 2,4-dicyanoglutarates Henkel Kommanditgesellschaft auf Aktien (DE) 1984-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10927071-B2 Process for preparing electron deficient olefins PCCA, COASY, LIG4 SLC1A2 1934/4885OR51E2 170/4885SLC1A3 1750/4885
US-10889542-B2 Process for preparing electron deficient olefins COASY, ACSL4, PCCA SLC1A2 2177/4885OR51E2 220/4885SLC1A3 2088/4885
US-10913707-B2 Process for preparing electron deficient olefins PCCA, ACSL4, COASY SLC1A2 1753/4885OR51E2 234/4885SLC1A3 1687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.