Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK2 | P49760 | 14/20 | 0.51 |
| ▸ | CLK3 | P49761 | 14/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 14/20 | 0.51 |
| ▸ | WNT1 | P04628 | 6/20 | 0.49 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17569146 | 0.92 | CLK2 (0.59) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL17569167 | 0.85 | CLK2 (0.59) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL17569138 | 0.85 | CLK2 (0.61) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL17587140 | 0.85 | CLK2 (0.66) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL17569132 | 0.84 | CLK2 (0.54) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL20747775 | 0.84 | WNT1 (0.45) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL17569148 | 0.83 | WNT1 (0.66) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL17569134 | 0.83 | CLK2 (0.55) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL17569150 | 0.83 | WNT1 (0.65) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL17587538 | 0.83 | CLK2 (0.56) | CLK2CLK3DYRK1AWNT1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9889140-B2 | 3-(1H-imidazo[4,5-C]pyridin-2-yl)-1H-pyrazolo[3,4-B]pyridine and therapeutic uses thereof | SAMUMED, LLC (US) | 2018-02-13 | — | — | US | disclosed |
| US-9889140-B2 | 3-(1H-imidazo[4,5-C]pyridin-2-yl)-1H-pyrazolo[3,4-B]pyridine and therapeutic uses thereof | SAMUMED, LLC (US) | 2018-02-13 | — | — | US | disclosed |