Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 9/20 | 0.61 |
| ▸ | CLK2 | P49760 | 8/20 | 0.61 |
| ▸ | CLK3 | P49761 | 7/20 | 0.61 |
| ▸ | WNT1 | P04628 | 11/20 | 0.54 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17569099 | 0.90 | WNT1 (0.67) | DYRK1ACLK2CLK3WNT1TGFBR1 | |
| SCHEMBL17569037 | 0.86 | DYRK1A (0.61) | DYRK1ACLK2CLK3WNT1TGFBR1 | |
| SCHEMBL17568968 | 0.85 | DYRK1A (0.61) | DYRK1ACLK2CLK3WNT1TGFBR1 | |
| SCHEMBL17569722 | 0.85 | WNT1 (0.55) | DYRK1ACLK2CLK3WNT1TGFBR1 | |
| SCHEMBL17569737 | 0.85 | WNT1 (0.60) | DYRK1ACLK2CLK3WNT1TGFBR1 | |
| SCHEMBL17568971 | 0.84 | CLK3 (0.66) | DYRK1ACLK2CLK3WNT1TGFBR1 | |
| SCHEMBL17568945 | 0.84 | CLK2 (0.73) | DYRK1ACLK2CLK3WNT1TGFBR1 | |
| SCHEMBL17555833 | 0.83 | CLK2 (0.85) | DYRK1ACLK2CLK3WNT1TGFBR1 | |
| SCHEMBL17583344 | 0.83 | CLK2 (0.78) | DYRK1ACLK2CLK3WNT1TGFBR1 | |
| SCHEMBL17569046 | 0.83 | DYRK1A (0.61) | DYRK1ACLK2CLK3WNT1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9889140-B2 | 3-(1H-imidazo[4,5-C]pyridin-2-yl)-1H-pyrazolo[3,4-B]pyridine and therapeutic uses thereof | SAMUMED, LLC (US) | 2018-02-13 | — | — | US | disclosed |
| US-9889140-B2 | 3-(1H-imidazo[4,5-C]pyridin-2-yl)-1H-pyrazolo[3,4-B]pyridine and therapeutic uses thereof | SAMUMED, LLC (US) | 2018-02-13 | — | — | US | disclosed |