Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17926115 | 0.92 | AR (0.35) | FADS1 | |
| SCHEMBL17926042 | 0.90 | FADS1 (0.36) | FADS1 | |
| SCHEMBL17926213 | 0.89 | FADS1 (0.34) | FADS1 | |
| SCHEMBL17925737 | 0.89 | AR (0.35) | — | |
| SCHEMBL17926221 | 0.86 | BACE1 (0.31) | FADS1 | |
| SCHEMBL17925936 | 0.85 | CHRM4 (0.33) | — | |
| SCHEMBL17926342 | 0.85 | — | — | |
| SCHEMBL17925815 | 0.85 | — | — | |
| SCHEMBL17926021 | 0.85 | — | — | |
| SCHEMBL17926023 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890167-B2 | Pyrazine compounds for the treatment of infectious diseases | HOFFMANN-LA ROCHE INC. (US) | 2018-02-13 | — | — | US | disclosed |
| US-9890167-B2 | Pyrazine compounds for the treatment of infectious diseases | HOFFMANN-LA ROCHE INC. (US) | 2018-02-13 | — | — | US | disclosed |