Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7591821 | 1.00 | BLM (0.52) | BLMKDM4CKDM4APHF8KDM2A | |
| SCHEMBL28051033 | 1.00 | BLM (0.52) | BLMKDM4CKDM4APHF8KDM2A | |
| SCHEMBL31268216 | 0.92 | BLM (0.60) | BLMKDM4CKDM4APHF8KDM2A | |
| Acrylic Acid SCHEMBL27774160 | 0.87 | BLM (0.42) | BLMKDM4CKDM4APHF8KDM2A | |
| SCHEMBL3613866 | 0.86 | GPR84 (0.46) | ACE2GPR84FFAR1MAPTLCK | |
| SCHEMBL28261795 | 0.86 | GPR84 (0.46) | ACE2GPR84FFAR1MAPTLCK | |
| SCHEMBL30018584 | 0.86 | GPR84 (0.46) | ACE2GPR84FFAR1MAPTLCK | |
| SCHEMBL30018402 | 0.86 | GPR84 (0.46) | ACE2GPR84FFAR1MAPTLCK | |
| SCHEMBL21073899 | 0.86 | GPR84 (0.46) | ACE2GPR84FFAR1MAPTLCK | |
| SCHEMBL9009694 | 0.86 | GPR84 (0.46) | ACE2GPR84FFAR1MAPTLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890198-B2 | Cyclosporin derivatives and uses thereof | S&T GLOBAL INC. (US) | 2018-02-13 | — | — | US | disclosed |