Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19850500 | 0.85 | USP2 (0.42) | USP2ACACBACACALMNAPLA2G2C | |
| SCHEMBL29020461 | 0.83 | LMNA (0.42) | USP2ACACBACACALMNAPLA2G2C | |
| SCHEMBL27058250 | 0.81 | USP2 (0.44) | USP2ACACBACACALMNAPLA2G2C | |
| SCHEMBL21226408 | 0.81 | USP2 (0.44) | USP2ACACBACACALMNAPLA2G2C | |
| SCHEMBL27058242 | 0.81 | USP2 (0.44) | USP2ACACBACACALMNAPLA2G2C | |
| SCHEMBL9743574 | 0.80 | LMNA (0.56) | USP2ACACBACACALMNAPLA2G2C | |
| SCHEMBL9743492 | 0.80 | LMNA (0.56) | USP2ACACBACACALMNAPLA2G2C | |
| SCHEMBL9743554 | 0.80 | LMNA (0.56) | USP2ACACBACACALMNAPLA2G2C | |
| SCHEMBL25246803 | 0.80 | LMNA (0.61) | USP2LMNAGPR84CYP2D6KDM4E | |
| SCHEMBL2935584 | 0.80 | LMNA (0.61) | USP2LMNAGPR84CYP2D6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890198-B2 | Cyclosporin derivatives and uses thereof | S&T GLOBAL INC. (US) | 2018-02-13 | — | — | US | disclosed |