Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19861296 | 0.91 | LMNA (0.30) | KMT2ALMNAHTT | |
| SCHEMBL15183543 | 0.89 | LMNA (0.35) | USP2KMT2ALMNAALDH1A1MEN1 | |
| SCHEMBL15183540 | 0.89 | LMNA (0.35) | USP2KMT2ALMNAALDH1A1MEN1 | |
| SCHEMBL19861221 | 0.89 | CHRM4 (0.39) | USP2KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL17524046 | 0.89 | USP2 (0.34) | USP2 | |
| SCHEMBL17524047 | 0.89 | USP2 (0.34) | USP2 | |
| SCHEMBL17523838 | 0.86 | USP2 (0.33) | USP2KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL17523839 | 0.86 | USP2 (0.33) | USP2KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL17523885 | 0.85 | LMNA (0.38) | USP2KMT2ALMNAALDH1A1MEN1 | |
| SCHEMBL17523886 | 0.85 | LMNA (0.38) | USP2KMT2ALMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890198-B2 | Cyclosporin derivatives and uses thereof | S&T GLOBAL INC. (US) | 2018-02-13 | — | — | US | disclosed |