Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 10/20 | 0.59 |
| ▸ | CA9 | Q16790 | 10/20 | 0.59 |
| ▸ | CA1 | P00915 | 9/20 | 0.59 |
| ▸ | CA2 | P00918 | 8/20 | 0.59 |
| ▸ | CA4 | P22748 | 4/20 | 0.53 |
| ▸ | CA6 | P23280 | 4/20 | 0.53 |
| ▸ | CA5A | P35218 | 4/20 | 0.53 |
| ▸ | CA7 | P43166 | 4/20 | 0.53 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19705422 | 0.93 | ALDH1A1 (0.56) | CA12CA9CA1CA2CA4 | |
| SCHEMBL19861593 | 0.88 | MEN1 (0.54) | CA12CA9CA1CA2LMNA | |
| SCHEMBL19401995 | 0.87 | CA12 (0.53) | CA12CA9CA1CA2CA4 | |
| SCHEMBL16267925 | 0.86 | HSD17B10 (0.50) | CA12CA9CA1CA2LMNA | |
| SCHEMBL20888759 | 0.86 | HSD17B10 (0.50) | CA12CA9CA1CA2CA4 | |
| SCHEMBL16267923 | 0.86 | HSD17B10 (0.50) | CA12CA9CA1CA2LMNA | |
| SCHEMBL13342994 | 0.86 | CYP3A4 (0.55) | CA12CA9CA1CA2LMNA | |
| SCHEMBL12476427 | 0.86 | HSD17B10 (0.50) | CA12CA9CA1CA2LMNA | |
| SCHEMBL12476425 | 0.86 | HSD17B10 (0.50) | CA12CA9CA1CA2LMNA | |
| SCHEMBL29730830 | 0.86 | HSD17B10 (0.50) | CA12CA9CA1CA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890176-B2 | Mannose derivatives for treating bacterial infections | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2018-02-13 | — | — | US | disclosed |