Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 8/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20227095 | 0.90 | DUT (0.38) | DUTPOLBHSD17B10PKMCRBN | |
| SCHEMBL19861772 | 0.89 | DUT (0.34) | DUTPOLBHSD17B10PKMCRBN | |
| SCHEMBL20227039 | 0.83 | DUT (0.34) | DUTPOLBHSD17B10PKMCRBN | |
| SCHEMBL19861892 | 0.80 | POLA1 (0.41) | — | |
| SCHEMBL19861900 | 0.80 | POLA1 (0.41) | — | |
| SCHEMBL20227076 | 0.79 | POLB (0.33) | DUTPOLBHSD17B10PKMCRBN | |
| SCHEMBL20227078 | 0.79 | POLB (0.33) | DUTPOLBHSD17B10PKMCRBN | |
| SCHEMBL19861755 | 0.79 | POLB (0.33) | DUTPOLBHSD17B10PKMCRBN | |
| SCHEMBL23171712 | 0.79 | POLB (0.35) | DUTPOLBHSD17B10PKMCRBN | |
| SCHEMBL19590313 | 0.79 | DUT (0.36) | DUTPOLBHSD17B10PKMCRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890188-B2 | Substituted nucleosides, nucleotides and analogs thereof | ALIOS BIOPHARMA, INC. (US) | 2018-02-13 | — | — | US | disclosed |