Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28115937 | 0.98 | ALDH1A1 (0.49) | HRH1CYP1A2ALDH1A1CYP2C19HRH3 | |
| SCHEMBL18098078 | 0.89 | CYP1A2 (0.51) | HRH1CYP1A2ALDH1A1CYP2C19HRH3 | |
| SCHEMBL3256822 | 0.88 | HRH1 (0.49) | HRH1CYP1A2ALDH1A1CYP2C19HRH3 | |
| Hydrochloric Acid SCHEMBL30593945 | 0.88 | ALDH1A1 (0.51) | HRH1CYP1A2ALDH1A1CYP2C19HRH3 | |
| SCHEMBL7678007 | 0.85 | HRH1 (0.57) | HRH1CYP1A2ALDH1A1CYP2C19HRH3 | |
| SCHEMBL12604331 | 0.84 | CYP1A2 (0.57) | HRH1CYP1A2ALDH1A1CYP2C19HRH3 | |
| SCHEMBL10399127 | 0.81 | HRH1 (0.53) | HRH1CYP1A2ALDH1A1CYP2C19HRH3 | |
| SCHEMBL10429959 | 0.81 | HRH1 (0.49) | HRH1CYP1A2ALDH1A1CYP2C19HRH3 | |
| SCHEMBL11877576 | 0.81 | HRH1 (0.56) | HRH1CYP1A2ALDH1A1CYP2C19HRH3 | |
| SCHEMBL22420959 | 0.81 | HRH1 (0.51) | HRH1CYP1A2ALDH1A1CYP2C19HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890178-B2 | Azabenzimidazoles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND UC (IE) | 2018-02-13 | — | — | US | disclosed |