Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 6/20 | 0.34 |
| ▸ | P2RY2 | P41231 | 5/20 | 0.34 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.33 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.33 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.33 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.33 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.33 |
| ▸ | DUT | P33316 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23996233 | 0.93 | TDP1 (0.34) | TDP1NT5EP2RY2P2RY6P2RY4 | |
| SCHEMBL17958879 | 0.93 | TDP1 (0.34) | TDP1NT5EP2RY2P2RY6P2RY4 | |
| SCHEMBL25400077 | 0.91 | TDP1 (0.39) | TDP1NT5EP2RY12P2RY2P2RY6 | |
| SCHEMBL25400083 | 0.91 | TDP1 (0.39) | TDP1NT5EP2RY12P2RY2P2RY6 | |
| SCHEMBL1097345 | 0.91 | TDP1 (0.42) | TDP1NT5EP2RY12P2RY2P2RY6 | |
| SCHEMBL25400092 | 0.91 | TDP1 (0.39) | TDP1NT5EP2RY12P2RY2P2RY6 | |
| SCHEMBL16993619 | 0.91 | TDP1 (0.39) | TDP1NT5EP2RY12P2RY2P2RY6 | |
| SCHEMBL16991644 | 0.91 | TDP1 (0.39) | TDP1NT5EP2RY12P2RY2P2RY6 | |
| SCHEMBL25400099 | 0.91 | TDP1 (0.39) | TDP1NT5EP2RY12P2RY2P2RY6 | |
| SCHEMBL25403028 | 0.87 | TSHR (0.35) | NT5EP2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180155384-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | ALIOS BIOPHARMA, INC. | 2018-06-07 | — | — | US | disclosed |
| US-9890188-B2 | Substituted nucleosides, nucleotides and analogs thereof | ALIOS BIOPHARMA, INC. (US) | 2018-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180155384-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | PNP, NT5C3B, NT5C2 | TDP1 354/4885NT5E 7/4885P2RY12 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.