Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.35 |
| ▸ | NPR3 | P17342 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23520088 | 0.88 | FOLH1 (0.35) | FOLH1NPR3ALDH1A1MEN1LMNA | |
| SCHEMBL22503353 | 0.88 | NPR3 (0.35) | FOLH1NPR3ALDH1A1MEN1LMNA | |
| SCHEMBL790021 | 0.86 | NPR3 (0.41) | FOLH1NPR3ALDH1A1MEN1LMNA | |
| SCHEMBL789730 | 0.86 | NPR3 (0.41) | FOLH1NPR3ALDH1A1MEN1LMNA | |
| SCHEMBL790384 | 0.86 | NPR3 (0.41) | FOLH1NPR3ALDH1A1MEN1LMNA | |
| SCHEMBL18649481 | 0.82 | NPR3 (0.32) | FOLH1NPR3 | |
| SCHEMBL19335150 | 0.78 | — | — | |
| SCHEMBL18877136 | 0.77 | NPR3 (0.34) | FOLH1NPR3ALDH1A1MEN1LMNA | |
| SCHEMBL21625918 | 0.76 | NPR3 (0.33) | FOLH1NPR3 | |
| SCHEMBL18671872 | 0.74 | TDP1 (0.34) | FOLH1NPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890188-B2 | Substituted nucleosides, nucleotides and analogs thereof | ALIOS BIOPHARMA, INC. (US) | 2018-02-13 | — | — | US | disclosed |