Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407376 | 0.82 | KMT2A (0.71) | KMT2AMEN1ACHEALDH1A1GAA | |
| SCHEMBL28037618 | 0.82 | KMT2A (0.71) | KMT2AMEN1ACHEALDH1A1GAA | |
| SCHEMBL8407328 | 0.80 | KMT2A (0.51) | KMT2AMEN1ACHEALDH1A1GAA | |
| SCHEMBL30575027 | 0.75 | ACHE (0.63) | KMT2AMEN1ACHEALDH1A1GAA | |
| SCHEMBL8371593 | 0.75 | ACHE (0.63) | KMT2AMEN1ACHEALDH1A1GAA | |
| SCHEMBL1513615 | 0.74 | FGFR1 (0.64) | FGFR1KMT2AMEN1BCL2FGFR2 | |
| SCHEMBL8407551 | 0.74 | TDP1 (0.67) | KMT2AMEN1ACHEALDH1A1GAA | |
| SCHEMBL8407455 | 0.73 | TDP1 (0.49) | KMT2AMEN1ACHEALDH1A1GAA | |
| SCHEMBL14144081 | 0.71 | ACHE (0.57) | KMT2AMEN1ACHEALDH1A1GAA | |
| SCHEMBL10547575 | 0.71 | MEN1 (0.61) | KMT2AMEN1ACHEALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9889131-B2 | Cadherin-11 inhibitors and methods of use thereof | GEORGETOWN UNIVERSITY (US) | 2018-02-13 | — | — | US | disclosed |