SCHEMBL19861930

SCHEMBL19861930

B/N=C\c1cc(-c2noc(C(F)(F)F)n2)ccc1C

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 17/20 0.44
HDAC6 Q9UBN7 14/20 0.44
HDAC1 Q13547 4/20 0.42
HDAC8 Q9BY41 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19861941 0.90 HDAC6 (0.44) HDAC4HDAC6HDAC1HDAC8
SCHEMBL19861940 0.85 HDAC4 (0.43) HDAC4HDAC6HDAC1HDAC8
SCHEMBL19861934 0.84 HDAC6 (0.49) HDAC4HDAC6HDAC1HDAC8
SCHEMBL20528695 0.77 HDAC4 (0.57) HDAC4HDAC6HDAC1HDAC8
SCHEMBL19861951 0.76 HDAC6 (0.42) HDAC4HDAC6HDAC1HDAC8
SCHEMBL24254417 0.76 HDAC6 (0.50) HDAC4HDAC6HDAC1HDAC8
SCHEMBL19864362 0.76 HDAC4 (0.50) HDAC4HDAC6HDAC1HDAC8
SCHEMBL19861924 0.76 HDAC6 (0.43) HDAC4HDAC6HDAC1HDAC8
Hydrochloric Acid SCHEMBL19859065 0.75 HDAC4 (0.49) HDAC4HDAC6HDAC1HDAC8
SCHEMBL19861944 0.74 HDAC6 (0.48) HDAC4HDAC6HDAC1HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018030460-A1 OXADIAZOLE COMPOUND AND USE THEREOF AS PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-15 WO disclosed