Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 11/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20528695 | 0.84 | HDAC4 (0.57) | HDAC6HDAC4HDAC1HDAC5HDAC8 | |
| SCHEMBL19864362 | 0.82 | HDAC4 (0.50) | HDAC6HDAC4S1PR1HDAC1HDAC5 | |
| SCHEMBL2888002 | 0.82 | HDAC4 (0.50) | HDAC6HDAC4S1PR1HDAC1HDAC8 | |
| Hydrochloric Acid SCHEMBL19859065 | 0.81 | HDAC4 (0.49) | HDAC6HDAC4S1PR1HDAC1HDAC5 | |
| SCHEMBL24254418 | 0.80 | HDAC4 (0.48) | HDAC6HDAC4HDAC1HDAC5HDAC8 | |
| SCHEMBL29395911 | 0.80 | HDAC4 (0.48) | HDAC6HDAC4HDAC1HDAC5HDAC8 | |
| SCHEMBL12267055 | 0.80 | L3MBTL1 (0.61) | S1PR1 | |
| SCHEMBL19042602 | 0.79 | HDAC4 (0.53) | HDAC6HDAC4HDAC8 | |
| SCHEMBL28679007 | 0.79 | HDAC6 (0.40) | HDAC6HDAC4HDAC1HDAC5HDAC8 | |
| SCHEMBL18824381 | 0.79 | HDAC4 (0.66) | HDAC6HDAC4HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022035763-A1 | BORON CONTAINING COMPOUNDS AND THEIR USES | 5METIS, INC. (US) | 2022-02-17 | — | — | WO | disclosed |