SCHEMBL19861936

SCHEMBL19861936

N/C(Cc1ccc(-c2noc(C(F)(F)F)n2)cc1)=N/O

nearest known ligand 0.62

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 11/20 0.62
HDAC6 Q9UBN7 18/20 0.60
HDAC1 Q13547 9/20 0.56
HDAC8 Q9BY41 9/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20645594 1.00 HDAC4 (0.62) HDAC4HDAC6HDAC1HDAC8
SCHEMBL20653962 0.84 HDAC4 (0.64) HDAC4HDAC6HDAC1HDAC8
SCHEMBL21581671 0.84 HDAC4 (0.72) HDAC4HDAC6HDAC1HDAC8
SCHEMBL21215272 0.81 HDAC4 (0.57) HDAC4HDAC6HDAC1HDAC8
SCHEMBL14645705 0.80 HDAC4 (0.74) HDAC4HDAC6HDAC1HDAC8
SCHEMBL19463719 0.79 HDAC6 (0.65) HDAC4HDAC6HDAC1HDAC8
SCHEMBL8360856 0.79 HDAC6 (0.60) HDAC4HDAC6HDAC1HDAC8
SCHEMBL20640857 0.78 HDAC4 (0.76) HDAC4HDAC6HDAC1HDAC8
SCHEMBL18824381 0.78 HDAC4 (0.66) HDAC4HDAC6HDAC1HDAC8
Bromide SCHEMBL29373726 0.77 HDAC6 (0.59) HDAC4HDAC6HDAC1HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10980233-B2 Oxadiazole compound and use thereof as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-04-20 US disclosed
US-20190230928-A1 OXADIAZOLE COMPOUND AND USE THEREOF AS PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-08-01 US disclosed
WO-2019012011-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2019-01-17 WO disclosed
WO-2018030460-A1 OXADIAZOLE COMPOUND AND USE THEREOF AS PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10980233-B2 Oxadiazole compound and use thereof as pesticides RXFP3, OXER1, OXA1L HDAC4 1699/4885HDAC6 1746/4885HDAC1 660/4885
US-20190230928-A1 OXADIAZOLE COMPOUND AND USE THEREOF AS PESTICIDES RXFP3, OXER1, OXA1L HDAC4 1699/4885HDAC6 1746/4885HDAC1 660/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.