SCHEMBL19861976

SCHEMBL19861976

Cc1ccsc1-c1cc2c3cccc4c5cccc6c7cc(-c8sccc8C)cc8c9cc(C(=O)O)cc%10c%11cc(C(=O)O)cc%12c(c1)c2c1c(c43)c(c56)c(c78)c(c%109)c1c%11%12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
CYP2A6 P11509 6/20 0.39
NPC1 O15118 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
NFKB1 P19838 1/20 0.38
RAB9A P51151 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
PAX8 Q06710 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CYP2E1 P05181 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2B6 P20813 1/20 0.36
CYP2C19 P33261 1/20 0.36
TTR P02766 1/20 0.36
PKM P14618 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6139747 0.77 KMO (0.51) MEN1KMT2ACYP2A6NPC1GAA
SCHEMBL16502516 0.70 MEN1 (0.48) MEN1KMT2ANPC1GAAMAPT
SCHEMBL28080232 0.66 MEN1 (0.49) MEN1KMT2ACYP2A6NPC1MAPT
SCHEMBL10012128 0.66 MEN1 (0.68) MEN1KMT2ANPC1MAPTRAB9A
SCHEMBL8442902 0.65 IL2 (0.57) MAPTSMN1; SMN2
SCHEMBL1821918 0.65 CYP2A6 (0.60) MEN1KMT2ACYP2A6CYP2E1CYP3A4
SCHEMBL58532 0.64 NR1H4 (0.58) NPC1MAPTRAB9A
SCHEMBL6067920 0.64 CYP2A6 (0.55) MEN1KMT2ACYP2A6GAAMAPT
SCHEMBL11478110 0.63 PTGS1 (0.59) KMT2ACYP2A6MAPTRAB9ASMN1; SMN2
SCHEMBL28115396 0.63 PTGS1 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180047906-A1 HEXABENZOCORONENE-BASED COMPOUND FOR ORGANIC PHOTOVOLTAIC CELLS UNIVERSITE DE PAU ET DES PAYS DE L'ADOUR (FR) 2018-02-15 US disclosed