SCHEMBL19861980

SCHEMBL19861980

CCCCCOc1ccsc1-c1ccc(-c2c(-c3ccccc3)c(-c3ccccc3)c(-c3ccc(-c4sccc4OCCCCC)cc3)c(-c3ccccc3)c2-c2ccccc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 4/20 0.40
LTA4H P09960 1/20 0.40
CNR2 P34972 1/20 0.39
PTPN1 P18031 2/20 0.39
THRA P10827 1/20 0.38
THRB P10828 1/20 0.38
MEN1 O00255 1/20 0.38
NR1I2 O75469 1/20 0.38
LMNA P02545 1/20 0.38
CHRM2 P08172 1/20 0.38
CYP3A4 P08684 1/20 0.38
ADRA2A P08913 1/20 0.38
MAPT P10636 1/20 0.38
OPRK1 P41145 1/20 0.38
HTR2B P41595 1/20 0.38
SLC6A3 Q01959 1/20 0.38
KMT2A Q03164 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
SOAT1 P35610 1/20 0.37
CYP1A2 P05177 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5831689 0.93 MEN1 (0.43) PTPN11LTA4HPTPN1THRATHRB
SCHEMBL8520184 0.81 MAPT (0.40) LTA4HTHRBMEN1NR1I2LMNA
SCHEMBL1279017 0.80 NR5A1 (0.43) LTA4HTHRBMEN1NR1I2LMNA
SCHEMBL5133914 0.80 NR5A1 (0.43) LTA4HTHRBMEN1NR1I2LMNA
SCHEMBL3103832 0.80 NR5A1 (0.43) LTA4HTHRBMEN1NR1I2LMNA
SCHEMBL22157987 0.78 KMT2A (0.44) LTA4HMEN1MAPTKMT2ACYP1A2
SCHEMBL19861974 0.75 DHFR (0.42) KMT2A
SCHEMBL19351841 0.74 MCHR1 (0.40) LTA4HMEN1NR1I2LMNACHRM2
SCHEMBL15401900 0.74 MCHR1 (0.40) LTA4HMEN1NR1I2LMNACHRM2
SCHEMBL19351456 0.71 MEN1 (0.40) CNR2MEN1NR1I2LMNACHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180047906-A1 HEXABENZOCORONENE-BASED COMPOUND FOR ORGANIC PHOTOVOLTAIC CELLS UNIVERSITE DE PAU ET DES PAYS DE L'ADOUR (FR) 2018-02-15 US disclosed