SCHEMBL19861981

SCHEMBL19861981

CCCCCOc1cc(Br)sc1Br

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 4/20 0.37
THRB P10828 4/20 0.37
SMPD1 P17405 4/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
TLR8 Q9NR97 2/20 0.36
PTPN11 Q06124 3/20 0.36
S1PR3 Q99500 1/20 0.36
MEN1 O00255 1/20 0.35
NR1I2 O75469 1/20 0.35
LMNA P02545 1/20 0.35
CHRM2 P08172 1/20 0.35
CYP3A4 P08684 1/20 0.35
ADRA2A P08913 1/20 0.35
MAPT P10636 1/20 0.35
OPRK1 P41145 1/20 0.35
HTR2B P41595 1/20 0.35
SLC6A3 Q01959 1/20 0.35
KMT2A Q03164 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28022174 0.98 SMPD1 (0.39) THRATHRBSMPD1TLR8PTPN11
SCHEMBL27946789 0.98 SMPD1 (0.39) THRATHRBSMPD1TLR8PTPN11
SCHEMBL13876361 0.98 SMPD1 (0.39) THRATHRBSMPD1TLR8PTPN11
SCHEMBL31464878 0.98 SMPD1 (0.39) THRATHRBSMPD1TLR8PTPN11
SCHEMBL4187002 0.98 SMPD1 (0.39) THRATHRBSMPD1TLR8PTPN11
SCHEMBL14842725 0.86 RARB (0.35) THRATHRBSMN1; SMN2TLR8MEN1
SCHEMBL14854547 0.86 RARB (0.38) SMN1; SMN2MEN1LMNACYP3A4MAPT
SCHEMBL2417770 0.84 SMPD1 (0.39) THRATHRBSMPD1TLR8PTPN11
SCHEMBL13876373 0.79 NCF1 (0.36) SMN1; SMN2LMNAMAPT
SCHEMBL28397542 0.77 SMPD1 (0.38) THRATHRBSMPD1PTPN11S1PR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180047906-A1 HEXABENZOCORONENE-BASED COMPOUND FOR ORGANIC PHOTOVOLTAIC CELLS UNIVERSITE DE PAU ET DES PAYS DE L'ADOUR (FR) 2018-02-15 US disclosed