Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18048845 | 0.99 | CTSL (0.45) | CTSLSIRT2PTGER4SIRT1SIRT5 | |
| SCHEMBL21627097 | 0.99 | CTSL (0.45) | CTSLSIRT2PTGER4SIRT1SIRT5 | |
| SCHEMBL21627023 | 0.99 | CTSL (0.45) | CTSLSIRT2PTGER4SIRT1SIRT5 | |
| SCHEMBL30990572 | 0.99 | CTSL (0.45) | CTSLSIRT2PTGER4SIRT1SIRT5 | |
| SCHEMBL16870074 | 0.99 | CTSL (0.45) | CTSLSIRT2PTGER4SIRT1SIRT5 | |
| SCHEMBL18048844 | 0.99 | CTSL (0.45) | CTSLSIRT2PTGER4SIRT1SIRT5 | |
| SCHEMBL18659588 | 0.98 | CTSL (0.47) | CTSLSIRT2PTGER4SIRT1SIRT5 | |
| SCHEMBL21627094 | 0.94 | CTSL (0.50) | CTSLSIRT2PTGER4SIRT1SIRT3 | |
| SCHEMBL21627095 | 0.94 | CTSL (0.50) | CTSLSIRT2PTGER4SIRT1SIRT3 | |
| SCHEMBL16869914 | 0.94 | CTSL (0.50) | CTSLSIRT2PTGER4SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10633415-B2 | Processes for preparing pharmaceutically relevant peptides | STEALTH BIOTHERAPEUTICS CORP (MC) | 2020-04-28 | — | — | US | disclosed |
| US-20180044378-A1 | PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES | STEALTH BIOTHERAPEUTICS INC. | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180044378-A1 | PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES | ADM2, VIP, PEPD | CTSL 188/4885SIRT2 3395/4885PTGER4 4803/4885 |
| US-10633415-B2 | Processes for preparing pharmaceutically relevant peptides | ADM2, VIP, PEPD | CTSL 188/4885SIRT2 3395/4885PTGER4 4803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.