SCHEMBL19862403

SCHEMBL19862403

Cc1ccc(O[Si](Oc2ccc(N3C(=O)c4ccc(Oc5ccc6c(c5)C(=O)N(c5ccc(Oc7ccc(N8C(=O)c9ccc(Oc%10ccc%11c(c%10)C(=O)N(C)C%11=O)cc9C8=O)cc7)cc5)C6=O)cc4C3=O)cc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.56
KMT2A Q03164 7/20 0.56
BRD4 O60885 1/20 0.48
MAPT P10636 3/20 0.46
NPSR1 Q6W5P4 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
ALDH1A1 P00352 4/20 0.46
GAA P10253 2/20 0.46
HTT P42858 1/20 0.46
LPAR1 Q92633 1/20 0.45
LPAR3 Q9UBY5 1/20 0.45
MCHR1 Q99705 1/20 0.43
NPC1 O15118 1/20 0.42
TSHR P16473 1/20 0.42
CASP1 P29466 1/20 0.42
RAB9A P51151 1/20 0.42
CASP7 P55210 1/20 0.42
HSD17B10 Q99714 1/20 0.42
PKM P14618 1/20 0.42
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL760105 0.86 MEN1 (0.64) MEN1KMT2ABRD4MAPTNPSR1
SCHEMBL19862404 0.85 MEN1 (0.55) MEN1KMT2ABRD4MAPTNPSR1
SCHEMBL5020550 0.85 MEN1 (0.65) MEN1KMT2ABRD4MAPTNPSR1
SCHEMBL13023418 0.84 MEN1 (0.61) MEN1KMT2ABRD4MAPTNPSR1
SCHEMBL13678848 0.82 MEN1 (0.69) MEN1KMT2ABRD4MAPTNPSR1
SCHEMBL14439307 0.82 BRD4 (0.62) MEN1KMT2ABRD4MAPTNPSR1
SCHEMBL757748 0.81 MEN1 (0.61) MEN1KMT2ABRD4MAPTNPSR1
SCHEMBL13899501 0.81 MEN1 (0.70) MEN1KMT2ABRD4MAPTNPSR1
SCHEMBL14010053 0.80 BRD4 (0.58) MEN1KMT2ABRD4MAPTNPSR1
SCHEMBL20149302 0.79 MEN1 (0.50) MEN1KMT2ABRD4MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180138510-A1 CATHODE ELECTRODE MATERIAL AND LITHIUM SULFUR BATTERY USING THE SAME TSINGHUA UNIVERSITY (CN) 2018-05-17 US disclosed
US-20180053938-A1 ELECTRODE BINDER, CATHODE ELECTRODE MATERIAL, AND LITHIUM ION BATTERY JIANGSU HUADONG INSTITUTE OF LI-ION BATTERY CO., LTD. (CN) 2018-02-22 US disclosed
US-20180047987-A1 ANODE ELECTRODE MATERIAL AND LITHIUM ION BATTERY USING THE SAME JIANGSU HUADONG INSTITUTE OF LI-ION BATTERY CO., LTD. (CN) 2018-02-15 US disclosed