SCHEMBL757748

SCHEMBL757748

Cc1ccc(-c2ccc(N3C(=O)c4ccc(Oc5ccc6c(c5)C(=O)N(C)C6=O)cc4C3=O)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.61
KMT2A Q03164 5/20 0.61
BRD4 O60885 1/20 0.56
ALDH1A1 P00352 4/20 0.52
NPC1 O15118 1/20 0.52
TSHR P16473 1/20 0.52
CASP1 P29466 1/20 0.52
RAB9A P51151 1/20 0.52
CASP7 P55210 1/20 0.52
HSD17B10 Q99714 1/20 0.52
NPSR1 Q6W5P4 2/20 0.49
MAPT P10636 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
HTT P42858 1/20 0.49
LPAR1 Q92633 1/20 0.48
LPAR3 Q9UBY5 1/20 0.48
CA9 Q16790 3/20 0.48
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
ESR1 P03372 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5020550 0.96 MEN1 (0.65) MEN1KMT2ABRD4ALDH1A1NPC1
SCHEMBL760105 0.94 MEN1 (0.64) MEN1KMT2ABRD4ALDH1A1NPC1
SCHEMBL13018338 0.93 MEN1 (0.53) MEN1KMT2ABRD4ALDH1A1NPC1
SCHEMBL13018340 0.93 MEN1 (0.53) MEN1KMT2ABRD4ALDH1A1NPC1
SCHEMBL13018341 0.93 MEN1 (0.53) MEN1KMT2ABRD4ALDH1A1NPC1
SCHEMBL25751090 0.93 MEN1 (0.53) MEN1KMT2ABRD4ALDH1A1NPC1
SCHEMBL7594849 0.92 MEN1 (0.54) MEN1KMT2ABRD4ALDH1A1NPC1
SCHEMBL13023418 0.92 MEN1 (0.61) MEN1KMT2ABRD4ALDH1A1NPC1
SCHEMBL14439307 0.90 BRD4 (0.62) MEN1KMT2ABRD4ALDH1A1NPC1
SCHEMBL12317361 0.89 BRD4 (0.60) MEN1KMT2ABRD4ALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8211558-B2 Crosslinked polymer electrolyte and method for producing same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-03 US disclosed
US-8138231-B2 Polymer having oxycarbon group, and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-20 US disclosed
US-20090274943-A1 CROSSLINKED POLYMER ELECTROLYTE AND METHOD FOR PRODUCING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-11-05 US disclosed
US-20090233142-A2 POLYMER HAVING OXOCARBON GROUP, AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-09-17 US disclosed
US-20090110995-A1 POLYMER HAVING OXYCARBON GROUP, AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-04-30 US disclosed
US-20070218335-A1 POLYMER HAVING OXOCARBON GROUP, AND USE THEREOF KAO CORPORATION (JP) 2007-09-20 US disclosed