SCHEMBL19862726

SCHEMBL19862726

c1ccc(-c2cc(-c3ccccc3)cc(-c3ccc(-c4c5ccccc5c(-c5ccc6c(c5)C(c5ccccc5)(c5ccccc5)c5ccccc5-6)c5ccccc45)nc3)c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 9/20 0.36
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
OPRK1 P41145 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B1 P14061 1/20 0.31
HSD17B2 P37059 1/20 0.31
FEN1 P39748 2/20 0.30
ALOX5AP P20292 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19862732 0.94 PDK2 (0.38) PDK2HSD17B1HSD17B2FEN1ALOX5AP
SCHEMBL19862729 0.90 PDK2 (0.41) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL26161307 0.88 PDK2 (0.36) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL26161247 0.88 PDK2 (0.42) PDK2MEN1LMNAMAPTKMT2A
SCHEMBL26161064 0.88 PDK2 (0.42) PDK2MEN1LMNAMAPTKMT2A
SCHEMBL26161244 0.88 PDK2 (0.42) PDK2MEN1LMNAMAPTKMT2A
SCHEMBL26161249 0.87 PDK2 (0.44) PDK2LMNA
SCHEMBL26161061 0.86 PDK2 (0.40) PDK2HSD17B1HSD17B2FEN1ALOX5AP
SCHEMBL26161067 0.85 PDK2 (0.45) PDK2LMNA
SCHEMBL15977744 0.85 PDK2 (0.38) PDK2KDM4EMAPTHSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190263735-A1 ORGANIC ELECTROLUMINESCENT DEVICE GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD . (CN) 2019-08-29 US disclosed
US-10347843-B2 Organic electronic material GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD. (CN) 2019-07-09 US disclosed
US-20180171218-A1 ORGANIC ELECTROLUMINESCENT DEVICE GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD . (CN) 2018-06-21 US disclosed
US-20180171218-A1 ORGANIC ELECTROLUMINESCENT DEVICE GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD . (CN) 2018-06-21 US disclosed
US-20180047909-A1 ORGANIC ELECTRONIC MATERIAL GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD . (CN) 2018-02-15 US disclosed
US-20180047909-A1 ORGANIC ELECTRONIC MATERIAL GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD . (CN) 2018-02-15 US disclosed
US-20180047910-A1 ORGANIC ELECTROLUMINESCENT DEVICE GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD . (CN) 2018-02-15 US disclosed
US-20180047910-A1 ORGANIC ELECTROLUMINESCENT DEVICE GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD . (CN) 2018-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180047909-A1 ORGANIC ELECTRONIC MATERIAL OCIAD1, OCIAD2, EED PDK2 3037/4885KDM4E 2521/4885MEN1 2920/4885
US-20190263735-A1 ORGANIC ELECTROLUMINESCENT DEVICE OCIAD1, OCIAD2, CTNND1 PDK2 2848/4885KDM4E 3296/4885MEN1 3758/4885
US-10347843-B2 Organic electronic material OCIAD1, OCIAD2, EED PDK2 3037/4885KDM4E 2521/4885MEN1 2920/4885
US-20180047910-A1 ORGANIC ELECTROLUMINESCENT DEVICE OCIAD1, OCIAD2, CTNND1 PDK2 2912/4885KDM4E 2575/4885MEN1 3797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.