SCHEMBL19862729

SCHEMBL19862729

c1ccc(C2(c3ccccc3)c3ccccc3-c3ccc(-c4c5ccccc5c(-c5ccc(-c6cc(-c7ccccn7)cc(-c7ccccn7)c6)cn5)c5ccccc45)cc32)cc1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.41
HPGDS O60760 1/20 0.33
KDR P35968 1/20 0.33
DHODH Q02127 1/20 0.32
CNR2 P34972 1/20 0.32
FEN1 P39748 4/20 0.31
CHEK2 O96017 1/20 0.31
ALOX5AP P20292 3/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
OPRK1 P41145 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
PIM1 P11309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19862731 0.93 PDK2 (0.44) PDK2HPGDSKDRDHODHCNR2
SCHEMBL19862717 0.91 PDK2 (0.44) PDK2KDRDHODHKDM4EMEN1
SCHEMBL19862726 0.90 PDK2 (0.36) PDK2FEN1ALOX5APKDM4EMEN1
SCHEMBL15977823 0.89 PDK2 (0.44) PDK2HPGDSKDRDHODHCNR2
SCHEMBL15977810 0.89 PDK2 (0.39) PDK2HPGDSKDRDHODHFEN1
SCHEMBL15977530 0.88 PDK2 (0.42) PDK2HPGDSKDRDHODHCNR2
SCHEMBL15977723 0.88 PDK2 (0.38) PDK2HPGDSKDRFEN1
SCHEMBL26161307 0.85 PDK2 (0.36) PDK2HPGDSFEN1ALOX5APKDM4E
SCHEMBL19862727 0.85 PDK2 (0.43) PDK2HPGDSKDRDHODHCNR2
SCHEMBL19862732 0.84 PDK2 (0.38) PDK2FEN1ALOX5AP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190263735-A1 ORGANIC ELECTROLUMINESCENT DEVICE GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD . (CN) 2019-08-29 US disclosed
US-10347843-B2 Organic electronic material GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD. (CN) 2019-07-09 US disclosed
US-20180171218-A1 ORGANIC ELECTROLUMINESCENT DEVICE GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD . (CN) 2018-06-21 US disclosed
US-20180171218-A1 ORGANIC ELECTROLUMINESCENT DEVICE GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD . (CN) 2018-06-21 US disclosed
US-20180047909-A1 ORGANIC ELECTRONIC MATERIAL GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD . (CN) 2018-02-15 US disclosed
US-20180047909-A1 ORGANIC ELECTRONIC MATERIAL GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD . (CN) 2018-02-15 US disclosed
US-20180047910-A1 ORGANIC ELECTROLUMINESCENT DEVICE GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD . (CN) 2018-02-15 US disclosed
US-20180047910-A1 ORGANIC ELECTROLUMINESCENT DEVICE GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD . (CN) 2018-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180047909-A1 ORGANIC ELECTRONIC MATERIAL OCIAD1, OCIAD2, EED PDK2 3037/4885HPGDS 4303/4885KDR 2256/4885
US-20190263735-A1 ORGANIC ELECTROLUMINESCENT DEVICE OCIAD1, OCIAD2, CTNND1 PDK2 2848/4885HPGDS 3735/4885KDR 1091/4885
US-10347843-B2 Organic electronic material OCIAD1, OCIAD2, EED PDK2 3037/4885HPGDS 4303/4885KDR 2256/4885
US-20180047910-A1 ORGANIC ELECTROLUMINESCENT DEVICE OCIAD1, OCIAD2, CTNND1 PDK2 2912/4885HPGDS 3952/4885KDR 1520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.