Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14970132 | 0.67 | LMNA (0.46) | LMNAALDH1A1RAB9A | |
| SCHEMBL10820358 | 0.65 | — | — | |
| SCHEMBL31484426 | 0.62 | TDP1 (0.35) | LMNAKMT2A | |
| SCHEMBL10908775 | 0.62 | — | — | |
| SCHEMBL92460 | 0.62 | — | — | |
| SCHEMBL21578086 | 0.61 | CSNK2A1 (0.41) | CSNK2A1CSNK2A2CSNK2BLMNAKDM4E | |
| SCHEMBL16702735 | 0.60 | NQO2 (0.42) | CSNK2A1LMNAKDM4EALDH1A1MAPT | |
| SCHEMBL11989005 | 0.60 | LMNA (0.34) | LMNA | |
| SCHEMBL11962984 | 0.60 | — | — | |
| SCHEMBL31484427 | 0.59 | LMNA (0.44) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018029159-A1 | ORGANIC SEMICONDUCTING COMPOUNDS COMPRISING A TETRAAZAPYRENE CORE | MERCK PATENT GMBH (DE) | 2018-02-15 | — | — | WO | disclosed |